Modifiers add specific settings to the game – from Execution Rules to More Enemies – that increase the challenge. Every Modifier that you turn on also increases the damage you take and the health of all enemies.
Advanced Modifiers are unlocked in order, so you must complete a Hive with all three Modifiers enabled to unlock the first Advanced Modifier. To unlock subsequent Advanced Modifiers, you must complete the Hive with latest unlocked Advanced Modifier. Note: only the latest unlocked Advanced Modifier is required to unlock the next Advanced Modifier.